Delete the selected song from your library and all playlists

`Option` + `Delete`

All hotkeys for iTunes (MacOS)

Playback shortcuts Start or stop playing the selected song	`Space`
Playback shortcuts Play the currently selected song from the beginning	`Enter`
Playback shortcuts Move forward or backward within a song	`Option` + `⌘` + `Arrow Right` / `Arrow Left`
Playback shortcuts Listen to the next or previous album in a list	`Option` + `Arrow Right` / `Arrow Left`
Playback shortcuts Go to the next or previous song in a list	`Arrow Left` / `Arrow Right`
Library and Playlist Select or deselect all the songs in a list	`⌘` +click the checkbox next to a song
Library and Playlist Create a new playlist from selected songs	`Shift` + `⌘` + `N`
Library and Playlist Create a new Smart Playlist	`Option` + `⌘` + `N`
Library and Playlist Delete the selected playlist without confirming that you want to delete it	`⌘` + `Delete`
Library and Playlist Delete the selected playlist and all the songs it contains from your library	`Option` + `Delete`
Library and Playlist Delete the selected song from your library and all playlists	`Option` + `Delete`
Library and Playlist Refresh the Radio list, when Radio is selected (or Genius Playlist if selected)	`⌘` + `R`
iTunes Store shortcuts Go to the next page / go to previous page in iTunes Store	`⌘` + `/`
iTunes Store shortcuts Initiate a search in the iTunes Store (from anywhere in iTunes)	Type in Search field and press Option+ `Enter`
iTunes Store shortcuts Check for app updates (when Apps is selected, below Library)	`⌘` + `R`
File and Window Change the song information columns	`Ctrl` +click a column heading
File and Window Expand or collapse all the triangles in the Radio’s Stream list	`⌘` +click a triangle
File and Window Shrink the iTunes window to show only the playback controls	`Option` + `⌘` + `M`
File and Window Switch between custom and maximum window sizes	`Option` +click the zoom button in the upper+left corner of the iTunes window
File and Window See the iTunes window resize while you are resizing it	`⌘` +drag the resize control in the lower+right corner of the window
File and Window In the Info window, see the info for the next or previous song in the list	`⌘` + `N` / `⌘` + `P`
File and Window Go to the previous or next pane in the Get Info or Preferences window	`Shift` + `⌘` + `/`
File and Window Select the search field	`⌘` + `F`
iTunes menu shortcuts Open iTunes Preferences	`⌘` + `,`
iTunes menu shortcuts Hide the iTunes window	`⌘` + `H`
iTunes menu shortcuts Hide all other applications	`Option` + `⌘` + `H`
iTunes menu shortcuts Quit iTunes	`⌘` + `Q`
File Menu Create a new playlist	`⌘` + `N`
File Menu Create a new playlist with the selected songs	`Shift` + `⌘` + `N`
File Menu Create a new Smart Playlist	`Option` + `⌘` + `N`
File Menu Open / add a file to your music library	`⌘` + `O`
File Menu Close the iTunes window	`⌘` + `W`
File Menu Open the Info window for the selected song or CD	`⌘` + `I`
File Menu Show where a song file is located	`Shift` + `⌘` + `R`
File Menu Show the currently playing song in the list	`⌘` + `L`
File Menu Stream audio file at a specific URL to iTunes	`⌘` + `U`
Edit Menu Open iTunes Preferences	`⌘` + `,`
Edit Menu Undo your last typing change while editing an item’s information	`⌘` + `Z`
Edit Menu Cut / Copy / Paste the selected song’s information or artwork	`⌘` + `X` / `⌘` + `C` / `⌘` + `V`
Edit Menu Select all the songs in the list	`⌘` + `A`
Edit Menu Deselect all the songs in the list	`Shift` + `⌘` + `A`
Edit Menu Hide or show the Artist and Album columns	`⌘` + `B`
Edit Menu Open the View Options window for the selected source	`⌘` + `J`
Add Menu Start or stop playing the selected song	`Space`
Add Menu Play the next song / play previous song in a list (When a song is playing)	`Arrow Right` / `Arrow Left`
Add Menu Increase the volume / decrease the volume	`⌘` + `Arrow Up` / `⌘` + `Arrow Down`
Add Menu Mute the sound (song keeps playing)	`Option` + `⌘` + `Arrow Down`
Add Menu Eject a CD	`⌘` + `E`
Visualizer Menu Turn the visualizer on or off	`⌘` + `T`
Visualizer Menu Fullscreen visualizer	`⌘` + `F`
Visualizer Menu See more options when a visual effect is showing	Press ?, then key available
Other Enter or exit full-screen view	`Ctrl` + `⌘` + `F`
Other Put the iTunes window in the Dock	`⌘` + `M`
Other Open iTunes Help	`⌘` + `?`
Other Open iTunes in “safe mode” (without external plug-ins)	`Option` + `Command` (while opening iTunes)
Other Choose artwork for the selected video	While the video is playing, Control+click the movie, and choose Set Poster Frame
Other Prevent iPod from automatically syncing when you connect it to your computer	Press and hold Option+Command when connecting iPod/iPhone
Other Go to the next or last chapter during spoken words (if available)	`Shift` + `⌘` + `Arrow Right` / `Arrow Left`