In the survival inventory tab of the creative inventory, Shift + clicking the X clears the whole inventory. In any other tab, Shift + clicking an item puts a stack into the hotbar

`↑ Shift` + `Mouse left click`

All hotkeys for Minecraft Java Edition

Non-configurable hotkeys Scroll through quick-bar and the chat when opened	`Mouse wheel up and down`
Non-configurable hotkeys Exit the chat / command window	`Esc`
Non-configurable hotkeys Toggle heads up display (HUD)	`F1`
Gameplay Take screenshot	`F2`
Non-configurable hotkeys In the survival inventory tab of the creative inventory, Shift + clicking the X clears the whole inventory. In any other tab, Shift + clicking an item puts a stack into the hotbar	`↑ Shift` + `Mouse left click`
Non-configurable hotkeys In the Multiplayer server selection menu, Shift + up and Shift + down moves a server name to a specific position. You can also hold shift while a server name is selected left click another server name and they will swap	`↑ Shift` + `↑ ↓`
Debug screen Toggle showing extra debug information	`F3`
Gameplay Hotbar slot	`1` - `9`
Debug screen Display less detailed graph	`0`
Debug screen Display Profiler graph	`↑ Shift` + `F3`
Debug screen Display Help menu that lists all F3 shortcuts	`F3` + `Q`
Debug screen Reload all chunks	`F3` + `A`
Debug screen Reload all textures, sounds and web-loaded client resources. This is useful for resource pack makers	`F3` + `T`
Debug screen Toggle the auto-pause when the window is out of focus	`F3` + `P`
Debug screen Toggle detailed item descriptions	`F3` + `H`
Debug screen Hold these keys at least for 6 seconds to trigger a manuel debug crash on purpose, after the keys are released	`F3` + `C`
Debug screen Toggle showing hitbox around entities	`F3` + `B`
Debug screen Clear chat history, including previous commands	`F3` + `D`
Debug screen Cycle the player's game mode between Creative and Spectator	`F3` + `N`
Debug screen Show the chunk boundaries immediately surrounding the player	`F3` + `G`
Configurable hotkeys Jump	`Space`
Configurable hotkeys (double tap) Toggle Fly Mode in Creative mode	`Space` then `Space`
Configurable hotkeys Sneak	`↑ Left Shift`
Configurable hotkeys Sprint	`Left Control`
Configurable hotkeys Strafe left	`A`
Configurable hotkeys Strafe right	`D`
Configurable hotkeys Walk backward	`S`
Configurable hotkeys Walk forward	`W`
Gameplay Attack / destroy	`Mouse left click`
Gameplay Pick block	`Mouse middle click`
Gameplay Use item / place block	`Mouse right click`
Gameplay Drop item	`Q`
Gameplay Drop whole stack of items. On Mac, use shortcut below, because this shortcut will quit game	`Ctrl` + `Q`
Gameplay (Mac) Drop whole stack of items	`Control` + `⌘ Cmd` + `Q`
Gameplay Open Inventory. Close any open GUI	`E`
Gameplay Swap items in hands	`F`
Gameplay Load toolbar activator	`X` + `1` - `9`
Gameplay Save toolbar activator	`C` + `1` - `9`
Gameplay (in chat window) Cycle through possible commands or arguments and also complete player names	`⭾ Tab`
Gameplay Open chat	`T`
Gameplay Open command (open the chat window with "/" character already typed")	`/`
Gameplay Advancements	`L`
Gameplay Toggle full screen	`F11`
Gameplay Toggle Perspective	`F5`