Close the iTunes window

`⌘ Cmd` + `W`

All hotkeys for iTunes 11 for Mac

Control menu Start or stop playing the selected song	`Space`
Playback Play the currently selected song from the beginning	`⤶ Enter`
Playback Move backward or forward within a song	`⌥ Option` + `⌘ Cmd` + `← →`
Playback Listen to previous or next album in a list	`⌥ Option` + `← →`
Playback Go to the previous or next song in a list	`← →`
File and window (on a triangle) Expand or collapse all the triangles in the Radio's Stream list	`⌘ Cmd` + `Mouse left click`
File menu Create a new playlist with the selected songs	`↑ Shift` + `⌘ Cmd` + `N`
File menu Create a new smart playlist	`⌥ Option` + `⌘ Cmd` + `N`
Library and playlist Delete the selected playlist without confirming that you want to delete it	`⌘ Cmd` + `Del`
Library and playlist Delete the selected song from your library and all playlists	`⌥ Option` + `Del`
iTunes Store Check for app updates (when Apps is selected, below the Library)	`⌘ Cmd` + `R`
iTunes Store Go to next page in the iTunes Store	`⌘ Cmd` + `]`
iTunes Store Go to previous page in the iTunes Store	`⌘ Cmd` + `[`
iTunes Store (after typing in Search field) Initiate a search in the iTunes Store	`⌥ Option` + `⤶ Enter`
File and window (on the video) Choose artwork for the selected video	`Control` + `Mouse left click`
File and window Shrink the iTunes window to show only the playback controls	`⌥ Option` + `⌘ Cmd` + `M`
File and window (on zoom button in the upper-left corner of the iTunes window) Switch between custom and maximum window sizes	`⌥ Option` + `Mouse left click`
File and window (drag the resize control in the lower-right corner of the window) See the iTunes window resize while you are resizing it	`⌘ Cmd` + `Mouse movement`
File menu Create a new playlist	`⌘ Cmd` + `N`
File and window In the Get Info window, see the info for the next or previous song in the list	`⌘ Cmd` + `P`
Visualizer menu Switch between viewing visual effects using the entire screen or in the iTunes window (when visualizer is on)	`⌘ Cmd` + `F`
File and window then press the indicated key to use an option (not all visual effects support this)	`?`
General (while opening iTunes) Open iTunes in “safe mode” (without external plug-ins)	`⌥ Option` + `⌘ Cmd`
Spoken word shortcuts Go to last or next chapter (if available)	`↑ Shift` + `⌘ Cmd` + `← →`
iTunes menu Open iTunes preferences	`Comamnd` + `,`
iTunes menu Hide the iTunes window	`⌘ Cmd` + `H`
iTunes menu Hide all other applications	`⌥ Option` + `⌘ Cmd` + `H`
iTunes menu Quit iTunes	`⌘ Cmd` + `Q`
File menu Add a file to your music library	`⌘ Cmd` + `O`
File menu Close the iTunes window	`⌘ Cmd` + `W`
File menu Open the song or CD Info window for the selected song or CD	`⌘ Cmd` + `I`
File menu Show where a song file is located	`↑ Shift` + `⌘ Cmd` + `R`
File menu Show the currently playing song in the list	`⌘ Cmd` + `L`
File menu Stream audio file at a specific URL to iTunes	`⌘ Cmd` + `U`
Edit menu Undo your last typing change while still in edit mode	`⌘ Cmd` + `Z`
Edit menu Cut the selected song’s information or artwork	`⌘ Cmd` + `X`
Edit menu Copy the selected song’s information or artwork	`⌘ Cmd` + `C`
Edit menu Paste the selected song’s information or artwork	`⌘ Cmd` + `V`
Edit menu Select all the songs in the list	`⌘ Cmd` + `A`
Edit menu Deselect all the songs in the list	`↑ Shift` + `⌘ Cmd` + `A`
Edit menu Hide or show the Artist and Album columns	`⌘ Cmd` + `B`
Edit menu Open the View Options window for the selected source	`⌘ Cmd` + `J`
Control menu When a song is playing, play the next song in a list	`→`
Control menu When a song is playing, play the previous song in a list	`←`
Control menu Increase the volume	`⌘ Cmd` + `↑`
Control menu Decrease the volume	`⌘ Cmd` + `↓`
Control menu Mute the sound (song keeps playing)	`⌥ Option` + `⌘ Cmd` + `↓`
Control menu Eject a CD	`⌘ Cmd` + `E`
Visualizer menu Turn the visualizer on or off	`⌘ Cmd` + `T`
Window menu Put the iTunes window in the Dock	`⌘ Cmd` + `M`
View menu Enter or exit full-screen view	`Control` + `⌘ Cmd` + `F`
Help menu Open iTunes help	`⌘ Cmd` + `?`