Notepad++

Edit menu

Block comment

Ctrl + ↑   Shift + K

All hotkeys for Notepad++

File menu
Open file

Ctrl + O

File menu
New file

Ctrl + N

File menu
Save file

Ctrl + S

File menu
Save as

Ctrl + Alt + S

File menu
Save all

Ctrl + ↑   Shift + S

File menu
Print

Ctrl + P

File menu
Exit

Alt + F4

File menu
Next document (also shows list of open files). Can be disabled - see Settings/Preferences/Global

Ctrl + ⭾ Tab

File menu
Previous document (also shows list of open files). Can be disabled - see above

Ctrl + ↑   Shift + ⭾ Tab

Search menu
...<keybs>5</keybs>: Jump down to next text marked. Use <keybs>0</keybs> for default found style

Ctrl + 1

File menu
Next document

Ctrl + Page Up

File menu
Previous document

Ctrl + Page Down

File menu
Close current document

Ctrl + W

Edit menu
Copy

Ctrl + C

Edit menu
Copy

Ctrl + Insert

Edit menu
Copy current line to clipboard

Ctrl + ↑   Shift + T

Edit menu
Cut

Ctrl + X

Edit menu
Cut

↑   Shift + Del

Edit menu
Paste

Ctrl + V

Edit menu
Paste

↑   Shift + Insert

Edit menu
Undo

Ctrl + Z

Edit menu
Undo

Alt + ⬅ Backspace

Edit menu
Redo

Ctrl + Y

Edit menu
Select all

Ctrl + A

Edit menu
Column mode select

Alt + ↑   Shift + ← ↑ → ↓

Edit menu
Column mode select

Alt + Mouse left click

Mouse gestures
(on fold point) Toggle collapsed state of this fold, and propagate below

Ctrl + Mouse left click

Edit menu
Column editor

Alt + C

Edit menu
Duplicate current line

Ctrl + D

Edit menu
Switch the current line position with the previous line position

Ctrl + T

Edit menu
Move current line or current selection if a single stream, up

Ctrl + ↑   Shift +

Edit menu
Move current line, or current selection if a single stream, Down

Ctrl + ↑   Shift +

Edit menu
Delete current line

Ctrl + L

Edit menu
Split lines

Ctrl + I

Edit menu
Join lines

Ctrl + J

Edit menu
Launch GoToLine dialog

Ctrl + G

Edit menu
Single line comment

Ctrl + Q

Edit menu
Single line uncomment

Ctrl + ↑   Shift + Q

Edit menu
Toggle single line comment

Ctrl + K

Edit menu
Block comment

Ctrl + ↑   Shift + K

Edit menu
(selection of one or more full lines) Insert tabulation or space (Indent)

⭾ Tab

Edit menu
(selection of one or more full lines) Remove tabulation or space (outdent)

↑   Shift + ⭾ Tab

Edit menu
Delete to start of word

Ctrl + ⬅ Backspace

Edit menu
Delete to end of word

Ctrl + Del

Edit menu
Delete to start of line

Ctrl + ↑   Shift + ⬅ Backspace

Edit menu
Delete to end of line

Ctrl + ↑   Shift + Del

Edit menu
Convert to lower case

Ctrl + U

Edit menu
Convert to UPPER CASE

Ctrl + ↑   Shift + U

Search menu
Go to matching brace (caret must be on a brace)

Ctrl + B

Edit menu
Launch CallTip ListBox

Ctrl + Space

Edit menu
Launch function completion ListBox

Ctrl + ↑   Shift + Space

Edit menu
Launch path completion ListBox

Ctrl + Alt + Space

Edit menu
Launch word completion ListBox

Ctrl + ⤶ Enter

Edit menu
Text direction RTL

Ctrl + Alt + R

Edit menu
Text Direction LTR

Ctrl + Alt + L

Incremental search widget
Next match (same as > button)

⤶ Enter

Incremental search widget
Previous match (same as < button)

↑   Shift + ⤶ Enter

Edit menu
Insert new unindented line above current

Ctrl + Alt + ⤶ Enter

Edit menu
Insert new unindented line below current

Ctrl + Alt + ↑   Shift + ⤶ Enter

Search menu
Launch find dialog

Ctrl + F

Search menu
Launch find and replace dialog

Ctrl + H

Search menu
Find next

F3

Search menu
Find previous

↑   Shift + F3

Search menu
Find in files

Ctrl + ↑   Shift + F

Search menu
Switch to search results window

F7

Search menu
Find (volatile) next

Ctrl + Alt + F3

Search menu
Find (volatile) previous

Ctrl + Alt + ↑   Shift + F3

Search menu
Select and find next

Ctrl + F3

Search menu
Select and find previous

Ctrl + ↑   Shift + F3

Search menu
Go to next found

F4

Search menu
Go to previous found

↑   Shift + F4

Search menu
Incremental search

Ctrl + ↑   Shift + I

Search menu
...<keybs>5</keybs>: Jump up to next text marked. Use <keybs>0</keybs> for default found style

Ctrl + ↑   Shift + 1

Search menu
Toggle bookmark

Ctrl + F2

Search menu
Go to next bookmark

F2

Search menu
Go to previous bookmark

↑   Shift + F2

Search menu
Select all between matching braces (caret must be on a brace)

Ctrl + Alt + B

View menu
Zoom in and zoom out

Ctrl + +

View menu
Zoom in and zoom out

Ctrl + -

View menu
Zoom in and zoom out

Ctrl + Mouse wheel up and down

View menu
Restore the original size from zoom

Ctrl + /

View menu
Toggle full screen mode

F11

View menu
Toggle post-it mode

F12

View menu
Collapse the current level

Ctrl + Alt + F

Run menu
Open in Safari

Ctrl + Alt + ↑   Shift + F

View menu
Fold all

Alt + 0

View menu
...to <keybs>8</keybs>: Collapse the level (1-8)

Alt + 1

View menu
Unfold all

Alt + ↑   Shift + 0

View menu
...<keybs>8</keybs> Uncollapse the level (1~8)

Alt + ↑   Shift + 1

Macro menu
Start to record / stop recording the macro

Ctrl + ↑   Shift + R

Macro menu
Play recorded macro

Ctrl + ↑   Shift + P

Macro menu
Trim trailing and save

Alt + ↑   Shift + S

Run menu
Launch run dialog

F5

Run menu
Get PHP help

Alt + F1

Run menu
Google search

Alt + F2

Run menu
Wikipedia search

Alt + F3

Run menu
Open file (name at cursor)

Alt + F5

Run menu
Open file in another instance (name at cursor)

Alt + F6

Run menu
Open in Chrome

Ctrl + Alt + ↑   Shift + R

Run menu
Open in Firefox

Ctrl + Alt + ↑   Shift + X

Run menu
Open in IE

Ctrl + Alt + ↑   Shift + I

Run menu
Send via Outlook

Ctrl + Alt + ↑   Shift + O

? menu
About

F1

? menu
Help contents

↑   Shift + F1

Mouse gestures
(on bookmark margin) Toggle bookmark

Mouse left click

Mouse gestures
(on fold point) Uncollapse this fold and all those below

↑   Shift + Mouse left click

Mouse gestures
Pop up context menu

Mouse right click

Mouse gestures
(on location pane, status bar) Go to line

Mouse double click

Mouse gestures
Select line

Mouse triple click

Similar combinations for other applications


RStudio
Compile PDF (TeX and Sweave)
Source

Ctrl + ↑   Shift + K


KiCad 5.0.2
Add Keepout Area
Pcbnew

Ctrl + ↑   Shift + K


GeoGebra
View/Hide CAS View
Windows shortcuts

Ctrl + ↑   Shift + K


Cisco Jabber
Toggle numeric keyboard
Active calls

Ctrl + ↑   Shift + K


Gitter
Show keyboard shortcuts
Global shortcuts

Ctrl + ↑   Shift + K


Siemens NX
Show
Edit menu

Ctrl + ↑   Shift + K


Winamp
Start/stop current visualization plug-In
General

Ctrl + ↑   Shift + K


draw.io
Insert ellipse
Document

Ctrl + ↑   Shift + K


Ace Editor
Find previous
Find / replace

Ctrl + ↑   Shift + K


Adobe Bridge CC
Creative Suite color settings
Edit menu

Ctrl + ↑   Shift + K


Evernote for Windows
Edit Hyperlink
Note Editor

Ctrl + ↑   Shift + K


Confluence
Use autocomplete for links
Autocomplete

Ctrl + ↑   Shift + K


Atom (Windows)
editor:delete-line
All shortcuts

Ctrl + ↑   Shift + K


Adobe Lightroom Classic
Show/hide image cells
Working in the Print module

Ctrl + ↑   Shift + K


Roll20
Move selected object to GM layer
Layers

Ctrl + ↑   Shift + K


Nuance Power PDF
Tile opened documents horizontally
Page

Ctrl + ↑   Shift + K


Adobe Premiere Pro (Windows)
Add Edit to All Tracks
Sequence

Ctrl + ↑   Shift + K


gedit
Clear highlight
Search

Ctrl + ↑   Shift + K


Microsoft Word 2016
Format letters as small capitals
Format characters

Ctrl + ↑   Shift + K


Corel Painter
Correct colors
Brush controls

Ctrl + ↑   Shift + K


AWS Cloud9 IDE (Windows)
Find Previous
Find

Ctrl + ↑   Shift + K


NetBeans
Previous word match
Navigating through source code

Ctrl + ↑   Shift + K


Comodo IceDragon
Web Console
Tools

Ctrl + ↑   Shift + K


IntelliJ IDEA (Windows, Linux)
Push commits
VCS / Local history

Ctrl + ↑   Shift + K


Mp3tag
Auto-numbering wizard (with counter reset for each subfolder)
General

Ctrl + ↑   Shift + K


LibreOffice Draw
Combines selected objects
Drawings

Ctrl + ↑   Shift + K


WriteMonkey
Delete line
Editing

Ctrl + ↑   Shift + K


Google Sheets
Input tools on/off  (available in spreadsheets in non-Latin languages)
Common actions

Ctrl + ↑   Shift + K


Microsoft Visual Studio 2017 (All shortcuts)
ArchitectureContextMenus.DirectedGraphContextMenu.NewComment
F# interactive

Ctrl + ↑   Shift + K


Maple
Insert Paragraph Before
Menu accelerators

Ctrl + ↑   Shift + K


Tumblr
Insert read-more link
Posting (Windows)

Ctrl + ↑   Shift + K


Sublime Text
Delete Line
Editing

Ctrl + ↑   Shift + K


Google Translator Toolkit
Open/close toolkit
Translation

Ctrl + ↑   Shift + K


KompoZer
Discontinue Link
Composition shortcuts

Ctrl + ↑   Shift + K


Freemind
Set link by file chooser
Node editing commands

Ctrl + ↑   Shift + K


Visual Studio Code (Linux)
Delete line
Basic editing

Ctrl + ↑   Shift + K


Visual Studio Code (Windows)
Delete line
Basic editing

Ctrl + ↑   Shift + K


Eclipse
Find next occurence of the search term
Search and replace

Ctrl + ↑   Shift + K


Outlook 2016 and Outlook 2013
Format letters as small capitals
Text formatting

Ctrl + ↑   Shift + K


Pushbullet (Chrome extension)
Dismiss the most recent notification
General

Ctrl + ↑   Shift + K


Slack
Direct messages menu
Navigation

Ctrl + ↑   Shift + K


SQL Server Management Studio (SSMS)
then <keybs>Ctrl</keybs> + <keybs>Shift</keybs> + <keybs>P</keybs>:  If the current bookmark is in a folder, moves to the next bookmark in the folder. Bookmarks outside the folder are skipped.  If the bookmark is not in a folder, moves to the next bookmark at the same level. If the Bookmarks window contains folder, bookmarks in folders are skipped.
Bookmark

Ctrl + ↑   Shift + K


Firefox Quantum
Web console
Tools

Ctrl + ↑   Shift + K


Zimbra Web Client
Strikethrough
HTML editor

Ctrl + ↑   Shift + K


Skype
Start a video call
Skype for Windows 10

Ctrl + ↑   Shift + K


Mozilla Thunderbird
Filter tasks
Lightning: Tasks tab

Ctrl + ↑   Shift + K


Audacity
Select > In All Tracks
Edit menu

Ctrl + ↑   Shift + K


Adobe Acrobat Reader DC
Tile all windows horizontally
Miscellaneous

Ctrl + ↑   Shift + K


Opera
Upload queued messages to mail server
E-mail keys: Reading and sending

Ctrl + ↑   Shift + K


Scrivener 1.9.9
Split with selection as name
Documents

Ctrl + ↑   Shift + K


Figma
Place image
Transform

Ctrl + ↑   Shift + K