Focus on the Elements content (this is strangely nowhere documented, but worked for me; without this one, you cannot use any of the other shortcuts below without clicking on the content first)

`Ctrl` + `Arrow Up`

All hotkeys for Google Chrome (Windows)

Manage Chrome DevTools - Accessing DevTools and DevTools Basics Open Developer Tools	`Ctrl` + `Shift` + `I` (or `F12` )
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Open Developer Tools (With Focus on Javascript Console)	`Ctrl` + `Shift` + `J`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Toggle Element Inspection mode	`Ctrl` + `Shift` + `C`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Switch Focus on Developer Tools (there is not really a shortcut for focusing on the Developer Tool, but this is a workaround. Watch the Inspector Mode Icon change color as you press for guidence. Finally, this works only if DevTools are docked; if they are not, simpy switch between windows with Alt+Tab)	`Ctrl` + `Shift` + `C` (2x)
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Show General Settings Dialog (press Esc to exit)	`?`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Switch to next / Switch to previous panel (add Alt to the combination to reverse the direction)	`Ctrl` + `[` / `]`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Dock / Undock Developer Tool	`Ctrl` + `D`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Toggle (mobile) Device Mode	`Ctrl` + `Shift` + `M`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Search Text in Source	`Ctrl` + `F`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Search Text across sources	`Ctrl` + `Shift` + `F`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Search by Filename	`Ctrl` + `O`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Zoom in / Zoom out Developer tools	`Ctrl` + `[` + `]` / `-`
Manage Chrome DevTools - Accessing DevTools and DevTools Basics Zoom to default	`Ctrl` + `0` (zero)
Manage Chrome DevTools - Elements Panel Focus on the Elements content (this is strangely nowhere documented, but worked for me; without this one, you cannot use any of the other shortcuts below without clicking on the content first)	`Ctrl` + `Arrow Up`
Manage Chrome DevTools - Elements Panel Navigate upwards/ downwards	`Arrow Up` / `Arrow Down`
Manage Chrome DevTools - Elements Panel Undo / Redo Change	`Ctrl` + `Z` / `Ctrl` + `Y`
Manage Chrome DevTools - Elements Panel Expand / Collapse	`Arrow Right` / `Arrow Left`
Manage Chrome DevTools - Elements Panel Expand node	Left-click on arrow
Manage Chrome DevTools - Elements Panel Expand/collapse node with all children	`Ctrl` + `Alt` +Left-click
Manage Chrome DevTools - Elements Panel Edit the element	`Enter`
Manage Chrome DevTools - Elements Panel Hide the element	`H`
Manage Chrome DevTools - Elements Panel Toggle edit as HTML	`F2`
Manage Chrome DevTools - Styles Panel Edit Rule	Left-click
Manage Chrome DevTools - Styles Panel Insert new property	Left-click on white space
Manage Chrome DevTools - Styles Panel Go to line of style rule property declaration	`Ctrl` +Left-click on property
Manage Chrome DevTools - Styles Panel Cycle through the color definition value	`Shift` +Left-click on property
Manage Chrome DevTools - Styles Panel Edit next / edit previous property	`Tab` / `Shift` + `Tab`
Manage Chrome DevTools - Styles Panel Increase / decrease value by 1	`Arrow Up` / `Arrow Down`
Manage Chrome DevTools - Styles Panel Increase / decrease value by 10	`Page Up` / `Page Down`
Manage Chrome DevTools - Styles Panel Increase / decrease value by 100	`Shift` + `Page Up` / `Page Down`
Manage Chrome DevTools - Styles Panel Increase / decrease value by 100	`Alt` + `Arrow Up` / `Arrow Down`
Manage Chrome DevTools - Sources Panel Pause / resume script execution	`F8` , `Ctrl` + `\`
Manage Chrome DevTools - Sources Panel Pause / resume script execution	`F8` , `Ctrl` + `\`
Manage Chrome DevTools - Sources Panel Step over next function call	`F10` , `Ctrl` + `'`
Manage Chrome DevTools - Sources Panel Step into next function call	`F11` , `Ctrl` + `;`
Manage Chrome DevTools - Sources Panel Step out of current function	`Shift` + `F11` , `Ctrl` + `Shift` + `;`
Manage Chrome DevTools - Sources Panel Select next / select previous call frame	`Ctrl` + `.` / `,`
Manage Chrome DevTools - Sources Panel Toggle breakpoint condition	Left-click on line-number
Manage Chrome DevTools - Sources Panel Edit breakpoint condition	Right-click on line number
Manage Chrome DevTools - Sources Panel Delete individual words	`Alt` + `Delete`
Manage Chrome DevTools - Sources Panel Comment a line or selected text	`Ctrl` + `/`
Manage Chrome DevTools - Sources Panel Save changes to local modifications	`Ctrl` + `S`
Manage Chrome DevTools - Sources Panel Save all changes	`Ctrl` + `Alt` + `S`
Manage Chrome DevTools - Sources Panel Go to line	`Ctrl` + `G`
Manage Chrome DevTools - Sources Panel Search by filename	`Ctrl` + `O`
Manage Chrome DevTools - Sources Panel Jump to line number	`Ctrl` + `P` +number
Manage Chrome DevTools - Sources Panel Jump to column	`Ctrl` + `O` +number +number
Manage Chrome DevTools - Sources Panel Go to member	`Ctrl` + `Shift` + `O`
Manage Chrome DevTools - Sources Panel Close active tab	`Alt` + `W`
Manage Chrome DevTools - Sources Panel Run snippet	`Ctrl` + `Enter`
Manage Chrome DevTools - Code Editor Go to matching bracket	`Ctrl` + `M`
Manage Chrome DevTools - Code Editor Jump to line number	`Ctrl` + `P` +number
Manage Chrome DevTools - Code Editor Jump to column	`Ctrl` + `O` +number +number
Manage Chrome DevTools - Code Editor Toggle comment	`Ctrl` + `/`
Manage Chrome DevTools - Code Editor Select next occurrence	`Ctrl` + `D`
Manage Chrome DevTools - Code Editor Undo last selection	`Ctrl` + `U`
Manage Chrome DevTools - Timeline Panel Start / stop recording	`Ctrl` + `E`
Manage Chrome DevTools - Timeline Panel Save timeline data	`Ctrl` + `S`
Manage Chrome DevTools - Timeline Panel Open / Load timeline data	`Ctrl` + `O`
Manage Chrome DevTools - Profiles Panel Start / stop recording	`Ctrl` + `E`
Manage Chrome DevTools - Console Panel Accept Suggestion	`Arrow Right`
Manage Chrome DevTools - Console Panel Previous / next command (line)	`Arrow Up` / `Arrow Down`
Manage Chrome DevTools - Console Panel Focus the Console	`Ctrl` + `
Manage Chrome DevTools - Console Panel Clear Console	`Ctrl` + `L`
Manage Chrome DevTools - Console Panel Multi-line entry	`Shift` + `Enter`
Manage Chrome DevTools - Console Panel Execute	`Enter`
Manage Tabs Open a new tab	`Ctrl` + `T`
Manage Tabs Reopen the last tab closed (up to 10 tabs)	`Ctrl` + `Shift` + `T`
Manage Tabs Close the tab(or close Chrome if only one tab is open)	`Ctrl` + `W` / `Ctrl` + `F4`
Manage Tabs Switch to the first tab, the second, etc.	`Ctrl` + `1` through `Ctrl` + `8`
Manage Tabs Switch to the last tab	`Ctrl` + `9`
Manage Tabs Switch to the next tab	`Ctrl` + `Tab` / `Ctrl` + `Page Up`
Manage Tabs Switch to the previous tab	`Ctrl` + `Shift` + `Tab` / `Ctrl` + `Page Down`
Manage Tabs Open a new window	`Ctrl` + `N`
Manage Tabs Open a new incognito window	`Ctrl` + `Shift` + `N`
Manage Tabs Close the current window	`Ctrl` + `Shift` + `W` / `Alt` + `F4`
Manage Tabs Open the link in a new background tab	`Ctrl` +left-click
Manage Tabs Open the link in a new foreground tab	`Ctrl` + `Shift` +left-click
Manage Tabs Open the link in a new window	`Shift` +left-click
Manage Tabs Download the link	`Alt` +left-click
Manage Tabs Open Google search in a new background tab	`Ctrl` + click on "Search Google for" from a drop down menu
Manage Tabs Open Google search in a new window	`Shift` + click on "Search Google for" from a drop down menu
Manage Tabs Open the link in the selected tab	Drag link to an existing tab
Manage Tabs Open the link in a new tab in the specified position on the tab strip	Drag link to tab bar
Manage Tabs Select multiple tabs (to rearrange them or create a new window)	Hold `Ctrl` + click on tabs in the tab bar
Manage Tabs Select all the tabs between two tabs (to rearrange them or create a new window)	Hold `Shift` + click on two tabs in the tab bar
Address Bar Set focus to the address bar (highlights the current webpage URL if available)	`Ctrl` + `L` / `Alt` + `D`
Address Bar Set focus to the toolbar	`Shift` + `Alt` + `T`
Address Bar Enter search query in the address bar	`Ctrl` + `E` / `Ctrl` + `K`
Address Bar Remove a prediction from the address bar	`Arrow Down` to highlight, then `Shift` + `Delete`
Address Bar Perform a search using the search engine associated with the keyword or the URI	Type search term and press `Enter`
Address Bar Open the site or a search in a new foreground tab	Type and press `Alt` + `Enter`
Address Bar Open the site or a search in a new background tab (doesn't work in Windows 10)	Type and press `Win` + `Enter`
Address Bar Open the site or a search in a new window	Type and press `Shift` + `Enter`
Address Bar Add www. to beginning and .com to end of input and open the web address in the current tab	Type and press `Ctrl` + `Enter`
Address Bar Add www. to beginning and .com to end of input and open the web address in a new foreground tab	Type and press `Ctrl` + `Alt` + `Enter`
Address Bar Add www. to beginning and .com to end of input and open the web address in a new background tab (doesn't work in Windows 10)	Type and press `Ctrl` + `Win` + `Enter`
Address Bar Add www. to beginning and .com to end of input and open the web address in a new window	Type and press `Ctrl` + `Shift` + `Enter`
Address Bar Tab-to-Search feature. E.g. Typing in 'yahoo.com' plus tab opens yahoo search. Add/edit search engines via 'Under the Hood' -> Basic -> Search Engines.	Type name of search engine and press `Tab`
View Webpages Alternate focus between address bar, bookmarks bar and webpage	`F6`
View Webpages Scroll down / scroll up	`Arrow Down` / `Arrow Up`
View Webpages Scroll one page down / up	`Page Down` / `Page Up`
View Webpages Scroll one page down / up	`Space` / `Shift` + `Space`
View Webpages Jump to beginning / to end of webpage	`Home` / `End`
View Webpages Zoom in / zoom out (or Ctrl+mousewheel)	`Ctrl` + `[` + `]` / `-`
View Webpages Return zoom to normal text size	`Ctrl` + `0` (zero)
View Webpages View webpage source	`Ctrl` + `U`
View Webpages Turn full screen on / off	`F11`
View Webpages Turn fullscreen on / off for some video types (e.g. YouTube)	`F`
View Webpages Mute / unmute some video types (e.g. YouTube)	`M`
Browse between Webpages Jump to homepage	`Alt` + `Home`
Browse between Webpages Jump to previous webpage visited / jump to next webpage	`Alt` + `Arrow Left` / `Arrow Right`
Browse between Webpages Reload current webpage	`F5` / `Ctrl` + `R`
Browse between Webpages Reload current webpage with cache override	`Ctrl` + `F5` / `Shift` + `F5`
Browse between Webpages Stop webpage loading	`Esc`
Browse within Webpages Jump to next / previous link	`Tab` / `Shift` + `Tab` with focus on webpage
Browse within Webpages Open link in current tab	`Enter` on link
Browse within Webpages Open link in a new background tab	`Ctrl` + `Enter` on link
Browse within Webpages Open link in a new foreground tab	`Shift` + `Ctrl` + `Enter` on link
Browse within Webpages Open link in a new window	`Shift` + `Enter` on link
Browse within Webpages Download link	`Alt` + `Enter` on link
Browse within Webpages Open context menu (simulate right mouse button)	`Shift` + `F10`
Browse within Webpages Select all content on webpage	`Ctrl` + `A`
Browse within Webpages Copy selected content to clipboard	`Ctrl` + `C` with content selected
Access Browser Features Print current webpage (Chrome Print Dialog)	`Ctrl` + `P`
Access Browser Features Print current webpage (Native Windows Print Dialog)	`Ctrl` + `Shift` + `P`
Access Browser Features Open file	`Ctrl` + `O`
Access Browser Features Save current webpage	`Ctrl` + `S`
Access Browser Features Open Wrench Menu (I'd call it file menu to remember the shortcut)	`Alt` + `F`
Access Browser Features Open History tab	`Ctrl` + `H`
Access Browser Features Open Downloads tab	`Ctrl` + `J`
Access Browser Features View Google Task manager	`Shift` + `Esc`
Access Browser Features Chrome Help	`F1`
Access Browser Features Open the Clear Browsing Data options	`Ctrl` + `Shift` + `Del`
Search Find text on webpage. Press Enter for.	`Ctrl` + `F` / `F3`
Search Find next / find previous match	`Enter` / `Shift` + `Enter` with text found on webpage
Search Find next / find previous match	`Ctrl` + `G` / `Ctrl` + `Shift` + `G` with text found on webpage
Search With focus on Search box: Close Search box	`Esc`
Bookmarks Shortcuts Show or hide bookmarks bar	`Ctrl` + `Shift` + `B`
Bookmarks Shortcuts Open Bookmark Manager	`Ctrl` + `Shift` + `O`
Bookmarks Shortcuts Add bookmark for current webpage	`Ctrl` + `D`
Bookmarks Shortcuts Saves all open pages as bookmarks in a new folder	`Ctrl` + `Shift` + `D`
Bookmarks Shortcuts Bookmark webpage (can be URL from address bar or link from page)	Drag URL to bookmark bar
Bookmarks Shortcuts Open Bookmark Manager Tab	`Alt` + `F` , then `B`