Python IDLE for Windows

File menu

Close current window

Alt + F4

All hotkeys for Python IDLE for Windows

File menu
Create a new editing window

Ctrl + N

File menu
Open an existing file

Ctrl + O

File menu
Open module

Alt + M

File menu
Show classes and methods in current file

Alt + C

File menu
Save current window to the associated file

Ctrl + S

File menu
Save current window to a new file, which becomes the associated file

Ctrl + ↑   Shift + S

File menu
Save current window to different file without changing the associated file

Alt + ↑   Shift + S

File menu
Print window

Ctrl + P

File menu
Close current window

Alt + F4

File menu
Close all windows and quit IDLE (asks to save if unsaved)

Ctrl + Q

Edit menu
Undo last change to current window (max 1000 changes)

Ctrl + Z

Edit menu
Redo last undone change to current window

Ctrl + ↑   Shift + Z

Edit menu
Copy selection into system-wide clipboard; then delete selection

Ctrl + X

Edit menu
Copy selection into system-wide clipboard

Ctrl + C

Edit menu
Insert system-wide clipboard into window

Ctrl + V

Edit menu
Select the entire contents of the edit buffer

Ctrl + A

Edit menu
Open a search dialog box with many options

Ctrl + F

Edit menu
Repeat last search

Ctrl + G

Edit menu
Find selection

Ctrl + F3

Edit menu
Find in files

Alt + F3

Edit menu
Open a search dialog box for searching files

Ctrl + H

Edit menu
Go to line

Alt + G

Edit menu
Show call tip

Ctrl + \

Edit menu
Show surrounding parents

Ctrl + 0

Edit menu
Show completions

Ctrl + Space

Edit menu
Build

Ctrl + B

Edit menu
Build

Ctrl + ↑   Shift + F10

Edit menu
Run the program

F5

Miscellaneous
Check module

Alt + X

Miscellaneous
Comment region

Alt + 3

Miscellaneous
Uncomment region

Alt + 4

Miscellaneous
Tabify region

Alt + 5

Miscellaneous
Untabify region

Alt + 6

Miscellaneous
Toggle auto coloring

Ctrl + /

Miscellaneous
Toggle tabs

Alt + T

Similar combinations for other applications

Microsoft Projects 2010 (Windows)
Close the Help window
Navigate Projects Help

Alt + F4

SharpDevelop 4.0 (Windows)
Exit SharpDevelop
Manage SharpDevelop Projects

Alt + F4

Access 2010 (Windows)
Close a dialog box
Manage Access Features - Dialog Boxes

Alt + F4

Unity3D 3 (Windows)
Quit
Window

Alt + F4

Unity3D 3 (MacOS)
Quit
Game Objects

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Firefox (Linux)
Close browser window
Firefox Windows

Ctrl + Shift + W / Alt + F4

Firefox (Windows)
Close browser window
Firefox Windows

Ctrl + Shift + W / Alt + F4

Google Chrome (Linux)
Close current window
Manage Tabs

Alt + F4

Tally 9.0 (Windows)
Purchase Order Voucher
Inventory Vouchers

Alt + F4

Total Commander 8 (Windows)
Exit | Minimize (with option MinimizeOnClose in wincmd.ini)
Main Shortcuts

Alt + F4

Inpage (Windows)
To quit application after closing document
For File Releated

Alt + F4

Notepad++ 5 (Windows)
Exit Notepad++
Basic File Management

Alt + F4

Access 2010 (Windows)
Close property dialog box
Manage Access Features - Pivot Table

Alt + F4

Evernote (Windows)
Close child windows and hide main window (minimize to tray). Or use Escape
Main Application Shortcuts - Managing Evernote

Alt + F4

Opera (Linux)
Close Opera
System

Ctrl + Shift + W / Alt + F4

Microsoft Windows 8 (Windows)
Shutdown Windows
Getting around Windows 8 Start Screen and Desktop

Alt + F4

Access 2010 (Windows)
Close a dialog box
Working with Text and Data - Dialog Boxes

Alt + F4

Microsoft Word 2007 (Windows)
Exit Office Word 2007.
Function key reference: ALT+Function key

Alt + F4

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Close property dialog box
Working with Text and Data - Pivot Table

Alt + F4

Notepad2 (Windows)
Exit
File Menu

Alt + F4

Access 2010 (Windows)
Close a dialog box
Working with Access Views - Dialog Boxes

Alt + F4

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Close property dialog box
Working with Access Views - Pivot Table

Alt + F4

Adobe Acrobat Pro (Windows)
Close Help window
Navigation - Navigating the Help window

Ctrl + W / Alt + F4

Notepad++ 6 (Windows)
Exit
File menu

Alt + F4

Microsoft Excel 2013 (Windows)
Close Excel
Manage Multiple Workbooks

Alt + F4

Linux Mint (Linux)
Close window
Current Application Window

Alt + F4

Microsoft Word 2013 (Windows)
Exit Word
The Rest

Alt + F4

Microsoft Windows 10 (Windows)
Close the current window
Windows Virtual Desktop/ Window Control

Alt + F4

Access 2010 (Windows)
Close a dialog box
The Rest - Dialog Boxes

Alt + F4

Skype for Business (Lync) 2016 (Windows)
Close the Conversation window
Conversation window

Alt + F4

Microsoft Excel 2010 (Windows)
Close Excel.
Manage Multiple Workbooks

Alt + F4

Console2 (Windows)
Exit Console
30 Shortcuts for Console2 (Windows)

Alt + F4

Safari Browser (MacOS)
Close the browser
General Shortcuts (Browser)

Alt + F4

Corel VideoStudio X9.5 (Windows)
Close
File Tab Operations

Alt + F4

Access 2010 (Windows)
Close property dialog box
The Rest - Pivot Table

Alt + F4

Microsoft Edge Browser (Windows)
Quit application (note: closing last remaining tab also quits application)
General

Alt + F4

Access 2016 (Windows)
Exit access 16
Design/Content Operation(on selected control)

Alt + F4

Microsoft PowerPoint 2016 (Windows)
Exit
Edit and General Text Operations

Alt + F4

Microsoft Visio 2016 (Windows)
Close the current window
Window/Navigation Shortcut

Alt + F4

Microsoft Visio 2016 (Windows)
Close help window
Window/Navigation Shortcut

Alt + F4

Access 2010 (Windows)
Quit/ exit Access
Manage Databases

Alt + F4

FileMaker Pro (Windows)
Exit or quit FileMaker Pro
General keyboard shortcuts (Windows)

Alt + F4 / Ctrl + Q

Finale (Windows)
Quit
File Menu

Ctrl + Q / Alt + F4

Dynamics AX 2015 (Windows)
Close the current form without saving changes.
Working with Forms

Esc / Alt + F4

Wondershare Editor (Windows)
Quit
Application control

Alt + F4

Microsoft Word 2016 (Windows)
Exit
General Operation

Alt + F4

Dynamics CRM 2015 (Windows)
Closes the snap-in console.
MMC Shortcuts(Microsoft Management Console)

Alt + F4

Dynamics NAV 2015 (Windows)
Close window or close program
Edit

Alt + F4

Dynamics AX 2015 (Windows)
Close the Help window.
General Shortcuts

Alt + F4

Microsoft Word 2016 (Windows)
Exit Office Word 2007.
All Function Key Shortcuts

Alt + F4

Adobe Acrobat Pro (MacOS)
Close Help window
Navigation - Navigating the Help window

Command + W / Alt + F4

Act! CRM (Windows)
Exit Act
General Shortcuts

Alt + F4

Microsoft Projects 2016 (Windows)
Close the program window.
Navigate Views and Windows

Alt + F4

Adobe XD (Experience Design) (Windows)
Quit
General Shortcuts

Alt + F4

Microsoft Excel 2016 (Windows)
Close Excel
The Rest

Alt + F4

Corel PhotoPaint X6 (Windows)
Exit
File Menu

Alt + F4

HTML-Kit (Windows)
Exit HTML-Kit Tools
87 Shortcuts for HTML-Kit (Windows)

Alt + F4

Corel Quattro Pro X8 (Windows)
Exit
File Menu

Alt + F4

Corel Ventura 10 (Windows)
Exit
General Shortcuts

Alt + F4

Corel Quattro Pro X8 (Windows)
Exit Quattro Pro
Function Keys

Alt + F4

Forte (Windows)
Exit agent
All Window

Alt + F4

TradeStation (Windows)
Close Application
Development Environment

Alt + F4

Soundforge (Windows)
Exit Sound Forge
Project File Shortcuts

Alt + F4

Tencent QQ Player (Windows)
Exit and Quit
30 Shortcuts for Tencent QQ Player (Windows)

Alt + F4

MetaTrader MT4 (Windows)
Close Client Terminal
Miscellaneous Shortcuts

Alt + F4

CA Client Automation (Windows)
Exit
File Menu

Alt + F4

Vegas Pro 14 (Windows)
Exit Vegas Pro
Project File

Alt + F4

XYplorer (Windows)
Exit
Navigation

Alt + F4

Teamcenter (Windows)
Exit Teamcenter
Miscellaneous Shortcuts

Alt + F4

KMPlayer (Windows)
Exit
General

Alt + F4

GOM Player (Windows)
Close
Others

Alt + F4 / Alt + X

Quickbooks Desktop (Windows)
Close Quickbooks
The Rest

Alt + F4

Tableau (Windows)
Closes the current workbook
General

Alt + F4

Solidworks 2019
Close Solidworks
Windows

Alt + F4

Spotify (Windows)
Quit
General

Alt + F4

Surfcam (Windows)
Exit SURFCAM
60 Shortcuts for Surfcam (Windows)

Alt + F4

Exact Audio Copy
Exit
File menu

Alt + F4

Xyplorer
Exit
File Menu

Alt + F4

progeCAD (Windows)
Closes all drawings and exits progeCAD
51 Shortcuts for progeCAD (Windows)

Alt + F4

Surfcam (Windows)
Exit the program
60 Shortcuts for Surfcam (Windows)

Alt + F4

Mastercam (Windows)
Exit Mastercam
53 Shortcuts for Mastercam (Windows)

Alt + F4

Vectorworks (Windows)
Exit
File Menu

Alt + F4 / Ctrl + Q

SpaceClaim (Windows)
Exit
71 Shortcuts for SpaceClaim (Windows)

Alt + F4

Altium Designer (Windows)
Close Altium Designer
Environment Shortcuts

Alt + F4

Sage Simply Accounting (Windows)
Close window or exit program
General

Alt + F4

Openbox
Close the active window
General

Alt + F4

LXDE
Close window
LDXE / Openbox

Alt + F4

DraftSight (Windows)
Exit Program
37 Shortcuts for DraftSight (Windows)

Alt + F4

GeoGebra
Quit GeoGebra
Windows shortcuts

Alt + F4

FlexiSign Pro 8.1 (Windows)
Exit
Other Shortcuts

Alt + F4

FlexiSign Pro 8.1 (MacOS)
Exit
Other Shortcuts

Alt + F4

SuperMemo (Windows)
Close Program
129 Shortcuts for SuperMemo (Windows)

Alt + F4

Tableau
Close the current workbook
Managing workbooks, sheets, and files (Tableau Desktop)

Alt + F4

Cisco Webex
Close any dialog box
Windows

Alt + F4

Google Chrome
Close the current window
Tab and window shortcuts

Alt + F4

Ubuntu
Close the window
Windows

Alt + F4

HitFilm
Exit
General

Alt + F4

Tibia
Try exiting game (this shortcut isn't listed in official manual)
Control Buttons

Alt + F4

QuickBooks Desktop
Exit
Opening / Closing QuickBooks

Alt + F4

Evernote for Windows
Close separate windows / Minimize main window to tray
Application-wide

Alt + F4

Xfce
Close window
Window manipulation

Alt + F4

Old School RuneScape (OSRS)
Close browser window. (This is browser/OS command, not a RuneScape hotkey)
General

Alt + F4

Alteryx
Close Alteryx Designer
Other shortcuts

Alt + F4

ProgeCAD
Exit
General

Alt + F4

PureSync
Exit
Actions menu

Alt + F4

CorelDRAW Graphics Suite 2018
Exit
General

Alt + F4

Logo Accounting
Close the program
General

Alt + F4

Bluebeam Revu
Close application
Advanced text

Alt + F4

Metapad
Exit Metapad
File menu

Alt + F4

Nuance Power PDF
Quit application
Application exit

Alt + F4

KMPlayer
Exit
General

Alt + F4

Windows PowerShell ISE
Exit
Starting and exiting

Alt + F4

Microsoft FrontPage
Quit Microsoft FrontPage.
Work with and manage Web pages

Alt + F4

Microsoft Paint
Close the window
Alt key menu

Alt + F4

Camtasia
Exit Theater
Camtasia Theater

Alt + F4

KDE Plasma Desktop
Close
Working with windows

Alt + F4

Linux Mint
Close the window
Frequently used shortcuts

Alt + F4

GNOME
Close window
Windows

Alt + F4

LightWave 3D
Show / hide motion paths
Layout: General

Alt + F4

PhraseExpress
Minimize / exit PhraseExpress
General

Alt + F4

Warcraft III
Exit Warcraft III
Menu commands

Alt + F4

Adobe XD (Windows)
Close
Keys for File menu

Alt + F4

Microsoft Word 2016
Exit Word
Alt + Function keys

Alt + F4

Microsoft Visual Studio 2017 (Most used shortcuts)
File.Exit
File

Alt + F4

Sweet Home 3D
Close
General

Alt + F4

Comodo IceDragon
Close window
Windows and Tabs

Alt + F4

Microsoft Visual Studio 2017 (All shortcuts)
File.Exit
File

Alt + F4

GIMP
Close the window
Dialogs

Alt + F4

WinHex
Exit
File menu

Alt + F4

WordPerfect X8
Quit WordPerfect
General

Alt + F4

LibreOffice
Closes the current document (close LibreOffice when the last open document is closed)
Controlling documents and windows

Alt + F4

Maple
Exit Maple
Menu accelerators

Alt + F4

FileMaker
Exit or quit FileMaker Pro
General

Alt + F4

WinNc
Quit
General

Alt + F4

NewsBin Pro
Close application
Standard Windows keyboard navigation

Alt + F4

Microsoft Access 2016
Exit Access
Miscellaneous keyboard shortcuts

Alt + F4

SQL Server Management Studio (SSMS)
Exit
Code editor

Alt + F4

ACDSee Free
Closes ACDSee Free
General

Alt + F4

7-Zip
Close the program
File menu

Alt + F4

Notepad++
Exit
File menu

Alt + F4

Paint.NET
Exit Paint.net
Toolbar

Alt + F4

Microsoft Excel 2016
Closes Excel
Function keys

Alt + F4

Windows 3.1
Close the application or dialog box
Common features

Alt + F4

WinSCP
Quit
Service commands

Alt + F4

Mozilla Thunderbird
Close window
Controlling Thunderbird windows and tabs

Alt + F4

GOM Player
Close
Others

Alt + F4

WhatsApp Web and Desktop
Exit app
General

Alt + F4

Spotify
Exit
General

Alt + F4

Opera
Close application window
Application windows

Alt + F4

Wordpad
Close WordPad
General

Alt + F4

Adobe Acrobat 2017 (Windows and Unix)
(Windows only) Close Help window
Help window

Alt + F4

Microsoft Projects 2007 (Windows)
Close the program window.
Navigate views and windows

Alt + F4

Gnome 3.0 (Linux)
Close current window.
Window Commands

alt + f4

Gnome 2.32 (Linux)
Close current window
Window Management

Alt + F4

Microsoft Windows Vista (Windows)
Close the active item or folder. Also will open "Shuts Down Windows" menu when on an empty desktop.
Work with Vista (Application) Windows

Alt + F4

Windows Media Player 11 (Windows)
Close WMP (default Windows feature).
Manage the Media Player Windows

Alt + F4

Microsoft Word 2010 (Windows)
Exit Word
The Rest

Alt + F4

Pinnacle Studio 22
Close application
General

Alt + F4